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As a laxative: Take 50-300 mg crystals in a single dose at night.
Detoxify: Take 50 mg Bitter Crystals daily with meals.
Other uses: Take 50 mg bitter crystals daily with meals. (A crystal of 50 mg is approximately the size of a match head. Larger crystals can easily be crushed into smaller crystals.) The smallest dose necessary to maintain regular bowel movement should be taken.