Cranberry Extract 4:1

Cranberry Extract 4:1

Cranberry extract is derived from the North American cranberry fruit, concentrated to a 4:1 ratio (4 parts fresh fruit to 1 part extract). It is best known for urinary tract health, though its benefits extend to antioxidant protection and cardiovascular support. The active compounds are primarily proanthocyanidins (PACs). Proanthocyanidins (type-A PACs), anthocyanins, quercetin, ursolic acid, benzoic acidPrevents urinary tract infections by inhibiting bacterial adhesion to uroepithelial cells Rich source of antioxidants protecting against oxidative stress Supports cardiovascular health through improved endothelial function Type-A proanthocyanidins create a conformational change in bacterial fimbriae (particularly E. coli), preventing adhesion to bladder and urethral lining polyphenols enhance nitric oxide production improving endothelial function flavonoids reduce LDL oxidation. Native American tribes used cranberry for bladder and kidney ailments, wounds, and fever early settlers adopted it for urinary complaints. UTI prevention (reduces recurrence by 35-40%), dental plaque reduction (prevents bacterial adhesion to teeth), gut health support (prebiotic effects), cardiovascular protection. PACs reach the urinary tract in active form absorption occurs in small intestine bioavailability enhanced with food 36mg PACs daily considered therapeutic dose for UTI prevention. Pairs well with D-mannose (enhanced UTI prevention synergy), vitamin C (immune support), probiotics (microbiome restoration). Best taken consistently daily for UTI prevention can be taken with or without food maintain adequate hydration. Generally safe mild GI upset possible theoretical interaction with warfarin (case reports, though limited evidence) caution in kidney stones (oxalate content). Look for 4:1 extract standardization to 36mg PACs per dose, cranberry fruit extract (not juice Capsules), third-party testing for PAC content.