Mix a small amount with other treatments in the palm of your hand and apply to face in the AM or the PM. A tingling sensation can be expected after application. Do not mix with formulations containing Niacinamide or EUK 134.
If topical Vitamin C is used as part of skin care, it should be applied at alternate times with EUK 134 or Niacinamide (ideally Vitamin C in the PM and EUK 134/Niacinamide in the AM). Otherwise, EUK 134/Niacinamide can affect the integrity of pure-form Vitamin C (L-Ascorbic Acid).